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FLASH GENE
Symbol VSIG2 contributors: - updated : 25-07-2005
HGNC name V-set and immunoglobulin domain containing 2
HGNC id 17149
Location 11q24      Physical location : 124.617.370 - 124.622.109
Synonym name cortical thymocyte receptor (X. laevis CTX) like
Synonym symbol(s) CTH, CTXL
DNA
TYPE functioning gene
STRUCTURE 4.00 kb     7 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveintestinelarge intestinecolon highly
 stomach   predominantly
Lymphoid/Immunelymph node   moderately
Reproductivemale systemprostate  highly
Respiratorylung   highly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a signal peptide
  • an extracellular Ig-like V-type (immunoglobulin-like) domain
  • an Ig-like C2-type (immunoglobulin-like) domain
  • a transmembrane region devoid of charged residues
  • a cytoplasmic tail
  • multiple N-glycosylation sites in the extracellular region
  • multiple phosphorylation sites in the cytoplasmic tail
  • conjugated GlycoP
    HOMOLOGY
    interspecies ortholog to murine Vsig2
    Homologene
    FAMILY
    CATEGORY immunity/defense
    SUBCELLULAR LOCALIZATION     plasma membrane
    text
  • type I membrane protein
  • basic FUNCTION invovled in antigen binding
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS immunity/defense
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein antigen
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS