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FLASH GENE
Symbol DGKG contributors: npt/ - updated : 15-12-2003
HGNC name diacylglycerol kinase, gamma 90kDa
HGNC id 2853
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • two N terminal EF hand calcium-binding domains
  • two phorbol esters/diacylglycerol binding domains (C1 domain)
  • a DAG catalytic domain
  • a DAG accessory domain
    • HOMOLOGY
    Homologene
    FAMILY
  • eukaryotic diacylglycerol kinase family
    • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    intracellular,nucleus
    basic FUNCTION
  • converting diacylglycerol to phosphatidic acid
    • CELLULAR PROCESS cell organization/biogenesis
    PHYSIOLOGICAL PROCESS
    text negatively regulating macrophage differentiation of leukemic cells
    PATHWAY
    metabolism
    signaling signal transduction
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding, nucleotide,
  • Ca2+
  • ATP
    • protein
    cell & other
    REGULATION
    activated by phosphatidylserine
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS