| overexpressed in the brain of Down syndrome fetuses | |
lack of MCIP1 exacerbated the hypertrophic response to activated calcineurin expressed from a muscle-specific transgene |
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RCAN1 knockout mice exhibited an attenuated mesenteric vasoconstriction to phenylephrine as compared with wild-type |
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H2O2 induces decrease in RCAN1 in hippocampal and cortical neurons |
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RCAN1-TG mice display T cell developmental defects in the thymus and peripheral immune tissues |
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modestly increased Rcan1 expression afforded by a single extra copy is sufficient to suppress pancreatic tumorigenesis mediated by oncogenic KrasG12D in mice through attenuation of calcineurin–NFAT signaling |