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FLASH GENE

Symbol

JSRP1

contributors: mlc/npt - updated : 11-01-2008

HGNC name	junctional sarcoplasmic reticulum protein 1
HGNC id	24963

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

EXPRESSION

Type	restricted

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Lymphoid/Immune spleen

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Muscular striatum skeletal

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains	a cytoplasmic domain
	a single transmembrane segment
	an intralumenal domain enriched in positively charged amino acids

HOMOLOGY

Homologene

FAMILY

CATEGORY

regulatory

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,cytoplasm,organelle,endoplasmic reticulum ,rough,smooth
text	skeletal muscle sarcoplasmic reticulum

basic FUNCTION	intracellular membrane compartment controling intracellular calcium concentration and therefore playing a role in excitation-contraction coupling
	involved in the molecular mechanism underlying skeletal muscle excitation-contraction coupling
	involved in the development or maintenance of skeletal muscle strength

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

interacting with the alpha1.1 subunit voltage-gated calcium channel and calsequestrin

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS