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FLASH GENE
Symbol PYGO1 contributors: - updated : 05-07-2005
HGNC name pygopus homolog 1 (Drosophila)
HGNC id 30256
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a PHD-type zinc finger
  • mono polymer complex
    HOMOLOGY
    interspecies ortholog to murine Pygo1
    Homologene
    FAMILY
    CATEGORY regulatory , transcription factor , signaling
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • involved in signal transduction through the Wnt pathway
  • playing a role in the regulation of transcription, DNA-dependent
  • CELLULAR PROCESS nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling signal transduction
    Wnt pathway
    a component
  • part of the nuclear beta-catenin/TCF complex
  • INTERACTION
    DNA
    RNA
    small molecule metal binding,
  • Zn2+
  • protein
  • BCL9 via The PHD-type zinc finger motif
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS