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FLASH GENE
Symbol ZNF593 contributors: - updated : 02-09-2005
HGNC name zinc finger protein 593
HGNC id 30943
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart   moderately
Lymphoid/Immunelymph node   highly
 spleen   predominantly
Nervousbrain   highly
Reproductivefemale systemplacenta  highly
Urinarybladder   moderately
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period pregnancy
Text placenta
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a C2H2-type zinc finger
    • HOMOLOGY
    Homologene
    FAMILY
    CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • negatively modulating the DNA binding activity of POU2F2 and therefore its transcriptional regulatory activity
  • could act either by binding to DNA octamer or by interacting with POU2F2
  • may also be a modulator of other octamer-binding proteins
    • CELLULAR PROCESS nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule metal binding,
  • Zn2+
    • protein
  • POU2F2
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS