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FLASH GENE
Symbol AOX1 contributors: - updated : 21-04-2007
HGNC name aldehyde oxidase 1
HGNC id 553
Location 2q33      Physical location : 201.450.730 - 201.536.215
Synonym symbol(s) AO, AOH1
EC.number 1.2.3.1
DNA
TYPE anonymous DNA segment
STRUCTURE 85.00 kb     35 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked   status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveliver   highly
Endocrineadrenal gland   highly
Nervousspinal cord    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Connectiveadipose  highly
Nervouscentral   
cells
SystemCellPubmedSpeciesStageRna symbol
Nervousglia
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
a 2Fe-2S ferredoxin-type domain
mono polymer homomer , dimer
HOMOLOGY
Homologene
FAMILY xanthine dehydrogenase family
CATEGORY enzyme
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm
basic FUNCTION can catalyze the formation of superoxide
CELLULAR PROCESS
PHYSIOLOGICAL PROCESS
PATHWAY
metabolism
signaling
a component
INTERACTION
DNA
RNA
small molecule metal binding, cofactor, nucleotide,
  • 2 2Fe-2S clusters
  • FAD
  • Molybdopterin
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS