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FLASH GENE
Symbol SGCB contributors: npt/ - updated : 30-04-2007
HGNC name sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
HGNC id 10806
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
conjugated GlycoP
HOMOLOGY
interspecies homolog to murine Sgcb
Homologene
FAMILY
  • sarcoglycan beta/delta/gamma/zeta family
    • CATEGORY structural protein
    SUBCELLULAR LOCALIZATION     plasma membrane
    text sarcolemma (type 2 membrane protein)
    basic FUNCTION
  • component of the sarcoglycan complex forming a link between the F-actin cytoskeleton and the extracellular matrix
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • associating with other sarcoglycans in a stoichiometrically equal complex
    • INTERACTION
    DNA
    RNA
    small molecule
    protein
  • dystrophin binding
  • utrophin, DP116, SGCE and SGCD in the Schwann cell membrane
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) LGMD2E
    related resource Limb-Girdle Muscular Dystrophy, Type 2E
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS