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FLASH GENE
Symbol TXNDC12 contributors: mct - updated : 08-06-2013
HGNC name thioredoxin domain containing 12 (endoplasmic reticulum)
HGNC id 24626
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a putative N-terminal signal sequence
  • a thioredoxin-like motif
  • C-terminal ER retention motif (EDEL)
    • HOMOLOGY
    interspecies homolog to C. elegans 2M531
    intraspecies homolog to ERP29, AGR2
    Homologene
    FAMILY thioredoxin superfamily
    CATEGORY enzyme , transport
    SUBCELLULAR LOCALIZATION extracellular
        intracellular
    intracellular,cytoplasm,organelle,lumen
    intracellular,cytoplasm,organelle,endoplasmic reticulum ,rough,smooth
    text secreted out of cell through trans-Golgi network (TGN)
    basic FUNCTION
  • having Trx enzymatic activity
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS electron transport
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS