Other morbid association(s)
|
Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
---|
tumoral
|  
| deletion
|  
|  
|
in sporadic colorectal cancer (early onset), putatively in Mt DNA metabolism | tumoral
| germinal mutation
|  
|  
|  
|
in early-onset colorectal cancer patients without family history and endometrial carcinoma | tumoral
|  
|  
| --low
|  
|
in cervical cancer | tumoral
|  
|  
|  
| loss of function
|
in colon and uterus tumor | tumoral
| germinal mutation
|  
|  
|  
|
associated with Lynch syndrome cancers (accountng for 10-20p100 of Lynch syndrome colorectal cancers) | tumoral
| germinal mutation
|  
|  
| loss of function
|
in patients with primary ovarian, fallopian tube, or peritoneal cancers | |