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FLASH GENE
Symbol NPFFR1 contributors: np - updated : 17-02-2006
HGNC name neuropeptide FF receptor 1
HGNC id 17425
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies homolog to murine Gm236
homolog to chimpanzee LOC466099
Homologene
FAMILY
  • G-protein coupled receptor 1 family
    • CATEGORY receptor membrane G
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • neuropeptide receptor activity
  • its activation led to intracellular Ca2+ mobilization in a concentration dependent manner
  • mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling signal transduction
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • NPFF receptor
    • cell & other
    REGULATION
    activated by neuropeptide FF
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS