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FLASH GENE

Symbol

ZNF536

contributors: SGE/npt - updated : 14-08-2009

HGNC name	zinc finger protein 536
HGNC id	29025

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

DNA

TYPE	functioning gene
STRUCTURE	185.64 kb     5 Exon(s)

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed NM_014717 5 - 4935 NP_055532 - 1300 - -

EXPRESSION

Type	restricted

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Nervous brain forebrain cerebral cortex       brain limbic system hippocampus       brain       highly   brain diencephalon hypothalamus       ganglia

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

nine C2H2-type zinc fingers

HOMOLOGY

interspecies	homolog to murine Zfp536 (88.8pc)
	homolog to rattus Znf536 (88.8pc)

Homologene

FAMILY

kruëppel C2H2-type zinc finger protein family

CATEGORY

transcription factor

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,nucleus

basic FUNCTION	involved in transcription
	negatively regulates neuron differentiation by repressing retinoic acid-induced gene transcription (Qin 2009)

CELLULAR PROCESS

nucleotide, transcription, regulation

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

binding

RNA

small molecule	metal binding,
	Zn2+

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS