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FLASH GENE
Symbol ST6GAL2 contributors: - updated : 30-03-2005
HGNC name ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
HGNC id 10861
PROTEIN
PHYSICAL PROPERTIES Hydrophobic
STRUCTURE
motifs/domains
  • an N-terminal hydrophobic sequence characteristic of type 2 transmembrane proteins
  • a stem region
  • sialyl motifs L (long)
  • sialyl motifs S (short)
  • sialyl motifs VS (very short)
  • four potential N-glycosylation sites
    • HOMOLOGY
    interspecies ortholog to rattus St6gal2
    ortholog to murine St6gal2
    intraspecies paralog to ST6GAL1
    Homologene
    FAMILY beta-galactoside alpha2, 6-sialyltransferase (ST6Gal) family
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,Golgi
    text
  • type 2 transmembrane protein
    • basic FUNCTION
  • catalyzing the transfer of sialic acid from CMP-sialic acid to an acceptor carbohydrate, usually to the terminal ends of carbohydrate chains
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism carbohydrate
    signaling
  • oligosaccharide metabolism
    • a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS