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FLASH GENE
Symbol NKX2-6 contributors: mct - updated : 05-07-2017
HGNC name NK2 transcription factor related, locus 6 (Drosophila)
HGNC id 32940
DNA
TYPE functioning gene
STRUCTURE 5.00 kb     3 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period embryo
Text caudal pharyngeal arches, branchial arch mesectoderm and ectoderm
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY
  • NK-2 homeobox family
    • CATEGORY transcription factor
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • may be playing a role in heart development, in the process of outflow tract
  • homeodomain transcription factor crucial for cardiovascular development
    • CELLULAR PROCESS nucleotide, transcription
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • complexing with NKX2-5, TBX and GATA family proteins
    • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) CART
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS