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FLASH GENE
Symbol MCF2L2 contributors: mct/npt - updated : 07-06-2008
HGNC name MCF.2 cell line derived transforming sequence-like 2
HGNC id 30319
Location 3q27.1      Physical location : 182.895.830 - 183.145.855
Synonym name
  • Rho family guanine-nucleotide exchange factor
  • MCF2-transforming sequence-like protein 2
    • Synonym symbol(s) KIAA0861, FLJ42509, DRG, DKFZp686K0690
    DNA
    TYPE functioning gene
    STRUCTURE 250.00 kb     30 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    30 - 4772 - 1114 - Takeuchi (2008)
    EXPRESSION
    Type widely
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestivemouth   highly
    Endocrinepancreasislet of Langerhans  lowly
    Lymphoid/Immunespleen   lowly
    Nervousbrain   highly
    Reproductivefemale systemovary  lowly
     male systemtestis  lowly
    Respiratoryrespiratory tractlarynx  highly
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Blood / hematopoieticbone marrow   
    Connectiveadipose  highly
    Muscularstriatumskeletal  
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    physiological period embryo, fetal, pregnancy
    Text cord blood
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    Homologene
    FAMILY
  • Rho family guanine-nucleotide exchange factor
    • CATEGORY unknown/unspecified
    SUBCELLULAR LOCALIZATION
    basic FUNCTION unknown
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility to type 2 diabetes
    Variant & Polymorphism SNP increasing the risk of type 2 diabetes
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS