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FLASH GENE
Symbol FASTK contributors: - updated : 14-02-2005
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a kinase domain
  • a proline-rich SH3-binding domain
  • HOMOLOGY
    interspecies homolog to murine Fastk
    Homologene
    FAMILY serine/threonine protein kinase family
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • phosphorylating and activating TIA1, resulting in induction of apoptosis
  • CELLULAR PROCESS cell life, cell death/apoptosis
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling signal transduction
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein binding to TIA1
    cell & other
    REGULATION
    activated by dephosphorylation
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS