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FLASH GENE
Symbol NANOS1 contributors: npt/ - updated : 04-02-2005
HGNC name nanos homolog 1 (Drosophila)
HGNC id 23044
Location 10q26.11      Physical location : 120.789.227 - 120.793.854
Synonym name
  • nanos homolog 1
  • EC_Rep1a
  • Synonym symbol(s) NOS1, NOS-1
    DNA
    TYPE functioning gene
    STRUCTURE 4.63 kb     1 Exon(s)
    MAPPING cloned Y linked N status provisional
    Physical map
    PNLIP 10q24-q26 pancreatic lipase PNLIPRP1 10q26.12 pancreatic lipase-related protein 1 PNLIPRP2 10q26.12 pancreatic lipase-related protein 2 MGC33547 10q26.12 hypothetical protein MGC33547 HSPA12A  heat shock 70kDa protein 12A LOC387712 10 similar to RIKEN cDNA 6430537H07 gene KIAA1598 10q26.12 KIAA1598 protein LOC387713 10 similar to ventral anterior homeobox 1 TRIK 10q26.12 TWIK-related spinal cord K+ channe SLC18A2 10q25 solute carrier family 18 (vesicular monoamine), member 2 LOC118987 10q26.12 hypothetical protein LOC118987 LOC387714 10 LOC387714 EMX2 10q26.1 empty spiracles homolog 2 (Drosophila) Rab11-FIP2 10q26.12 KIAA0941 protein C10orf5 10q26.12 chromosome 10 open reading frame 5 FLJ13188 10q26.12 hypothetical protein FLJ13188 GPR10 10q25.3-q26 G protein-coupled receptor 10 LOC390007 10 similar to Mitochondrial import receptor subunit TOM22 homolog (Translocase of outer membrane 22 kDa subunit homolog) (hTom22) (1C9-2) C10orf46 10q26.12-q26.13 chromosome 10 open reading frame 46 LOC88066 10q26.13 similar to 60S ribosomal protein L17 (L23) NANOS1 10q26.13 nanos homolog 1 (Drosophila) EIF3S10 10q26 eukaryotic translation initiation factor 3, subunit 10 theta, 150/170kDa SFXN4 10q26.12 sideroflexin 4 PRDX3 10q25-q26 peroxiredoxin 3 GPRK5 10q24-qter G protein-coupled receptor kinase 5 RGS10 10q25 regulator of G-protein signalling 10 TIAL1 10q26.11 TIA1 cytotoxic granule-associated RNA binding protein-like 1 LOC119563 10q26.13 similar to 40S ribosomal protein S8 BAG3 10q25.2-q26.2 BCL2-associated athanogene 3 LOC93202 10q26.13 thioredoxin 1 pseudogene 2 INPP5F 10q26.13 inositol polyphosphate-5-phosphatase F FLJ13081 10q26.13 hypothetical protein FLJ13081 SEC23IP 10q25-q26 SEC23 interacting protein LOC338570 10q26.13 similar to alpha NAC/1.9.2. protein LOC196051 10q26.13 hypothetical protein LOC196051 WDR11 10q26 WD repeat domain 11
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    1 - 4627 - 292 - Jaruzelska (2003)
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Reproductivemale systemtestis   
    Skeletonaxial skeletonskullfacemaxilla 
    cells
    SystemCellPubmedSpeciesStageRna symbol
    Reproductivespermatocyte
    Reproductivespermatogonia
    Skin/Tegumentmelanocyte
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    physiological period fetal
    Text eye
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • one nanos-type zinc finger
  • HOMOLOGY
    Homologene
    FAMILY
  • nanos family
  • CATEGORY RNA associated , transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    text concentrated in the perinuclear region
    basic FUNCTION
  • may regulate translation of specific mRNAs by forming a complex with PUM2 that associates
  • with the 3' untranslated regions (UTRs) of mRNA targets
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA binding
    small molecule
    protein
  • interacting with PUM2
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS