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FLASH GENE
Symbol SNRNP40 contributors: npt/ - updated : 22-11-2005
HGNC name small nuclear ribonucleoprotein 40kDa (U5)
HGNC id 30857
Location 1p35.2      Physical location : 31.732.416 - 31.769.644
Synonym name
  • WD repeat domain 57 (U5 snRNP specific)
  • prp8, U5 snRNP-specific 40 kDa protein
  • U5 snRNP-specific 40 kDa protein (hPrp8-binding)
  • 38 kDa-splicing factor
  • Synonym symbol(s) SPF38, PRPF8BP, HPRP8BP, WDR57, 40K, FLJ41108, MGC1910, RP11-490K7.3
    DNA
    TYPE functioning gene
    STRUCTURE 37.23 kb     10 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    10 - 1638 - 357 - -
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Nervousbrain    
    Reproductivefemale systemuterus   
     male systemprostate   
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Epithelialbarrier liningendometrium  
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • 63 N-terminal amino acids
  • 7 WD40 repeats
  • HOMOLOGY
    Homologene
    FAMILY
    CATEGORY RNA associated
    SUBCELLULAR LOCALIZATION extracellular
    basic FUNCTION
  • likely mediating regulated protein-protein interactions
  • CELLULAR PROCESS cell life
    cell communication
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • component of the U5 small nuclear ribonucleoprotein (snRNP) particle
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
  • interacting with PRPF38
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS