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FLASH GENE
Symbol PSMG2 contributors: npt - updated : 16-11-2005
HGNC name proteasome (prosome, macropain) assembly chaperone 2
HGNC id 24929
Location 18p11.21      Physical location : 12.703.063 - 12.725.737
Synonym name
  • proteasome assembling chaperone-2
  • tumor necrosis factor superfamily, member 5-induced protein 1
  • CD40 ligand-activated specific transcript 3
  • HCCA3 protein
  • hepatocellular carcinoma susceptibility protein
  • Synonym symbol(s) HCCA3, CLAST3, MDS003, HsT1707, MGC15092, PAC2, TNFSF5IP1
    DNA
    TYPE functioning gene
    STRUCTURE 22.00 kb     7 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    7 - 1064 - 264 - -
    EXPRESSION
    Type ubiquitous
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Reproductivefemale systemuteruscervix moderately
     male systemtestis  moderately
    Urinarybladder   predominantly
     kidney   highly
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Blood / hematopoieticbone marrow   
    cell lineage
    cell lines
    fluid/secretion blood
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • two N-glycosylation sites
  • three N-myristoylation sites
  • several phosphorylation sites
  • mono polymer heteromer , dimer
    HOMOLOGY
    interspecies ortholog to murine Tnfsf5ip1
    ortholog to rattus Tnfsf5ip1_predicted
    ortholog to chicken TNFSF5IP1
    Homologene
    FAMILY
  • PSMG2 family
  • CATEGORY regulatory
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • involved in the maturation of 20S proteasomes
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • heterodimer PSMG1 and PSMG2
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS