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FLASH GENE
Symbol HDGFRP3 contributors: mct - updated : 20-06-2006
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart   moderately
Endocrineneuroendocrinepituitary  highly
 parathyroid   highly
Nervousbrain   predominantly
Reproductivefemale systemovary  moderately
 male systemtestis  predominantly
Respiratorylung   highly
Visualeyeanterior segmentiris  
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a well-conserved amino acid sequence at the N-terminus (the HATH region)
  • a putative bipartite nuclear localizing signal (NLS) sequence in a similar location in its self-specific region of HDGF
    • HOMOLOGY
    Homologene
    FAMILY
  • HDGF family
    • CATEGORY signaling growth factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • may function mainly in the nucleus of the brain, testis, and heart, probably for cell proliferation
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS