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FLASH GENE
Symbol SH3BGR contributors: - updated : 29-04-2004
HGNC name SH3 domain binding glutamic acid-rich protein
HGNC id 10822
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a proline-rich region containing the consensus sequence of a SH3 domain
  • a carboxy-terminal glutamic acid rich region,putatively assuming a coiled-coil structure
    • HOMOLOGY
    interspecies homolog to murine Sh3brg
    homolog to C.elegans ZK856.10
    homolog to C.elegans R05F9.10
    Homologene
    FAMILY SH3BRG family
    CATEGORY adaptor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria
    intracellular,cytoplasm,organelle,membrane
    intracellular,nucleus
    basic FUNCTION SH3/SH2 adaptor protein,involved in protein complex assembly
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component maybe a part of a multimeric complex (Scartezzini,97)
    INTERACTION
    DNA
    RNA
    small molecule
    protein SH3 domain binding
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS