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FLASH GENE

Symbol

GGN

contributors: mct - updated : 29-06-2022

HGNC name	gametogenetin
HGNC id	18869

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

SPGF69

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --over   in bladder cancer tissues compared to the control and was associated with the unsatisfactory survival rate of patients

Susceptibility

Variant & Polymorphism

Candidate gene
Marker	might serve as a biomarker, for CRC
Therapy target
	System Type Disorder Pubmed cancer digestive colon therapeutic target for Colorectal cancer

ANIMAL & CELL MODELS

pachytene spermatocytes of the Ggn heterozygous knockout mice showed an increased incidence of unrepaired DNA double strand breaks (DSBs)