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FLASH GENE
Symbol EXOSC4 contributors: - updated : 20-12-2004
HGNC name exosome component 4
HGNC id 18189
Location 8q24.3      Physical location : 145.133.521 - 145.135.550
Synonym name
  • exosome complex exonuclease RRP41
  • ribosomal RNA-processing protein 41
  • Synonym symbol(s) SKI6, p12A, RRP41, Ski6p, RRP41A, Rrp41p, FLJ20591
    DNA
    TYPE functioning gene
    STRUCTURE 2.00 kb     3 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    Homologene
    FAMILY RNAse PH family
    CATEGORY RNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    intracellular,nucleus,nucleolus
    basic FUNCTION
  • required for the 3'processing of the 7s pre-RNA to the mature 5.8s rRNA
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • component of the mRNA decay complex (LSM1, LSM3, LSM4, EXOSC2, EXOSC4, EXOSC10, PARN, XRN1, CCRN4L, UPF1, UPF2, UPF3B)
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS