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FLASH GENE
Symbol ARHGAP27 contributors: - updated : 30-12-2005
HGNC name Rho GTPase activating protein 27
HGNC id 31813
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • an Src homology 3 (SH3) domain
  • multiple WW domains, a proline-rich region
  • a PH domain and a RhoGAP domain
    • HOMOLOGY
    Homologene
    FAMILY
    CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    intracellular,nucleus
    basic FUNCTION may be playing a role in clathrin-mediated endocytosis
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein binding protein for SH3KBP1 (its second SH3 domain binds to a proline-rich region of ARHGAP27)
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS