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FLASH GENE
Symbol NEXMIF contributors: mct - updated : 09-10-2017
HGNC name neurite extension and migration factor
HGNC id 29433
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
HOMOLOGY
Homologene
FAMILY
CATEGORY regulatory
SUBCELLULAR LOCALIZATION     intracellular
intracellular,nucleus
text
  • highly expressed in postmitotic neuronsv
    • basic FUNCTION
  • may play a role in postmitotic, maturing neurons
  • may participate in neural circuit formation during developmental stages via nuclear and cytoplasmic KIAA2022
  • major role in neuron development and brain function, and is essential for proper brain development
  • regulates cell-cell and cell-matrix adhesion and cellular migration by regulating the expression of adhesion molecules
  • plays important roles in the control of neuronal migration and morphogenesis
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) AUTSX7 , MRX98 , DUPXQ13
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    constitutional        
    disrupted in a pericentric inversion in two mentally retarded brothers
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS