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FLASH GENE
Symbol NEXMIF contributors: mct - updated : 09-10-2017
HGNC name neurite extension and migration factor
HGNC id 29433
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Nervousbrainforebraincerebral cortex highly Homo sapiensFetal
 brainhindbraincerebellum  
Reproductivefemale systemovary   
Urinarykidney    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Nervousperipherous  highly Homo sapiens
cells
SystemCellPubmedSpeciesStageRna symbol
Nervousneuron Homo sapiens
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period fetal
Text brain
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
HOMOLOGY
Homologene
FAMILY
CATEGORY regulatory
SUBCELLULAR LOCALIZATION     intracellular
intracellular,nucleus
text
  • highly expressed in postmitotic neuronsv
    • basic FUNCTION
  • may play a role in postmitotic, maturing neurons
  • may participate in neural circuit formation during developmental stages via nuclear and cytoplasmic KIAA2022
  • major role in neuron development and brain function, and is essential for proper brain development
  • regulates cell-cell and cell-matrix adhesion and cellular migration by regulating the expression of adhesion molecules
  • plays important roles in the control of neuronal migration and morphogenesis
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) AUTSX7 , MRX98 , DUPXQ13
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    constitutional        
    disrupted in a pericentric inversion in two mentally retarded brothers
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS