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FLASH GENE

Symbol

NES

contributors: npt/mct/shn - updated : 01/11/2012

HGNC name	nestin
HGNC id	7756

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --over   in prostate cancer cells from patients with lethal androgen-independent disease

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS

nestin-deficient mice have a normal development of the central nervous system but show impaired motor coordination the number of acetylcholine receptor clusters, the nerve length, and the endplate bandwidth are significantly increased in neuromuscular junction area