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FLASH GENE

Symbol

KCNJ6

contributors: mct/npt/pgu - updated : 26-02-2015

HGNC name	potassium inwardly-rectifying channel, subfamily J, member 6
HGNC id	6267

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

TRI21 , KPLBS

Susceptibility

Variant & Polymorphism

Candidate gene	could be a candidate for other lipodystrophies
Marker
Therapy target

ANIMAL & CELL MODELS

	GIRK subunits are present in most of the 5-HT(1A) receptor-expressing cells in hippocampus, cerebral cortex, septum, and dorsal raphe nucleus in rat brain
	Girk2 null mice are fertile, the male weaver transgenic mice carrying a gain-of-function mutation in the Girk2 gene are infertile