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FLASH GENE

Symbol

SEMA3F

contributors: mct - updated : 30-10-2018

HGNC name	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
HGNC id	10728

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --low   in metastatic tumor tumoral     --low   in lung cancer

Susceptibility

Variant & Polymorphism

Candidate gene
Marker	semaphorin 3F amniotic level at 16-18 weeks of gestation was reduced in women who subsequently developed preeclampsia compared to women with a normal pregnancy
Therapy target
	System Type Disorder Pubmed neurosensorial visual degenerative use of SEMA3F in protecting the outer retina against subretinal neovascularization.

ANIMAL & CELL MODELS