Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Ensembl
	HGNC	UniGene	Nucleotide	OMIM	UCSC

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FLASH GENE

Symbol

PDIA6

contributors: mct - updated : 24-05-2019

HGNC name	protein disulfide isomerase-associated 6
HGNC id	30168

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral         of PDIA6 significantly decreased the volume of giant cell tumors of bone (GCTB) tumoral     --over   in bladder cancer

Susceptibility

Variant & Polymorphism

Candidate gene
Marker	may serve as a biomarker and therapeutic target for non-small cell lung cancer (NSCLC)patients
	alterations in PDIA3/PDIA6 expression levels may be involved in the breast carcinogenic process and should be further investigated as a marker of aggressiveness
Therapy target
	System Type Disorder Pubmed cancer lung   PDIA6 may serve as a therapeutic target for Non-small cell lung cancer (NSCLC) patients cancer brain   may be considered an attractive and potent target for the treatment of glioblastoma cancer urinary   could be targeted for the treatment of bladder cancer

ANIMAL & CELL MODELS