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FLASH GENE
Symbol CES3 contributors: mct - updated : 22-03-2018
HGNC name carboxylesterase 3 (brain)
HGNC id 1865
Location 16q11.2      Physical location : 66.995.131 - 67.009.051
Synonym name triacylglycerol hydrolase
Synonym symbol(s) Br3, TGH
EC.number 3.1.1.1
DNA
TYPE functioning gene
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a 18-amino acid signal peptide
  • two asparagine residues in the N-X-S/T motif thought to function as a putative N-glycosylation site
  • an endoplasmic reticulum retention motif (HXEL-COOH)
    • HOMOLOGY
    Homologene
    FAMILY
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,lumen
    intracellular,cytoplasm,organelle,endoplasmic reticulum ,rough,smooth
    basic FUNCTION
  • major adipocyte lipase
  • may be playing a role in lipid metabolism and/or the blood-brain barrier system
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS