Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Orphanet | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | SLC6A19 | contributors: mct/npt/pgu - updated : 21-11-2012 |
HGNC name | solute carrier family 6 (neurotransmitter transporter), member 19 |
HGNC id | 27960 |
|
EXPRESSION |
Type | restricted |
cell lineage |
cell lines |
fluid/secretion |
at STAGE |
PROTEIN |
PHYSICAL PROPERTIES |
STRUCTURE |
motifs/domains
![]() | |
![]() |
conjugated | GlycoP |
HOMOLOGY |
interspecies | ortholog to murine Slc6a19 |
Homologene |
FAMILY |
CATEGORY | transport carrier |
SUBCELLULAR LOCALIZATION
| plasma membrane |
basic FUNCTION | |
![]() | |
![]() |
CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism |
signaling |
a component |
INTERACTION |
DNA |
RNA |
small molecule |
protein | ![]() |
![]() | |
![]() | |
![]() |
cell & other |
REGULATION |
activated by | JAK2 (up-regulates SLC6A19 activity which may foster amino acid uptake into JAK2 expressing cells) ![]() | |
Other | regulation of SLC6A19 by ACE2 and collectrin (TMEM27) (ACE2 and TMEM27 modify the sensitivity of SLC6A19 to regulation by kinases) ![]() |
ASSOCIATED DISORDERS |
corresponding disease(s) | HND |
Susceptibility | to arterial hypertension |
Variant & Polymorphism repeat | minisatellites MS7 may be a risk factor for hypertension ![]() |
![]() |
Candidate gene |
Marker |
Therapy target |
ANIMAL & CELL MODELS |
![]() |