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FLASH GENE

Symbol

NME8

contributors: mct - updated : 12-11-2017

HGNC name	NME/NM23 family member 8
HGNC id	16473

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

ICS6

Susceptibility

to osteoarthritis to neurodegeneration (Alzheimer disease)

Variant & Polymorphism SNP	significant associations between 5' SNPs and osteoarthritis that hint at regulatory functions
	NME8 rs2718058 appears to play a role in lowering the brain neurodegeneration

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS