Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol GPR148 contributors: mct - updated : 29-08-2015
HGNC name G protein-coupled receptor 148
HGNC id 23623
Location 2q21.2      Physical location : 131.486.642 - 131.487.909
Synonym name
  • brain and testis restricted GPCR
  • Synonym symbol(s) PGR6, BTR
    DNA
    TYPE functioning gene
    STRUCTURE 2.39 kb     1 Exon(s)
    regulatory sequence
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    1 - 1937 - 347 - 2003 12679517
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Nervousbrain     Homo sapiens
    Reproductivemale systemtestis    Homo sapiens
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • extracellular N terminus
  • seven transmembrane regions,
  • an intracellular C terminus and transduce extracellular signals through heterotrimeric GTP-binding proteins, G-proteins
  • HOMOLOGY
    Homologene
    FAMILY family 1 of G-protein coupled receptors
    CATEGORY receptor membrane G
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • one of the several different receptors for 5- hydroxytryptamine (serotonin), involved in G-protein coupled receptor protein signaling pathway
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    constitutional   deletion    
    with ARHGEF4 in developmental delay (DD)/intellectual disability (ID),attention-deficit hyperactivity disorder
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS