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FLASH GENE
Symbol GPR133 contributors: mct - updated : 13-09-2011
HGNC name G protein-coupled receptor 133
HGNC id 19893
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a GPS domain
  • a PTX domain
  • a seven transmembrane region (7tm_2)
    • HOMOLOGY
    interspecies homolog to murine Gpr133 (80.83 pc)
    Homologene
    FAMILY
  • G-protein coupled receptor 2 family, adhesion GPCR subfamily
  • LN-TM7 subfamily
    • CATEGORY adhesion , receptor membrane G
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • may be involved in neuropeptide signaling pathway
  • novel gene associated with adult height
  • adhesion G-protein-coupled receptor group V, with large genomic size, multiple introns, and a fascinating flora of functional domains
  • activates the Gs protein/adenylyl cyclase pathway
  • must functionally interact with a G protein to mediate intracellular inositol phosphate formation
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling signal transduction
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS