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FLASH GENE

Symbol

ZNF462

contributors: mct - updated : 23-08-2012

HGNC name	zinc finger protein 462
HGNC id	21684

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

DNA

TYPE	functioning gene
STRUCTURE	148.43 kb     13 Exon(s)

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed NM_021224 13 - 8306 NP_067047 - 2506 - 2011 21570965

EXPRESSION

Type

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Reproductive male system prostate       Skin/Tegument skin         Urinary kidney

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains	thirteen c2h2-type zinc fingers
	one krab domain

HOMOLOGY

Homologene

FAMILY

krüppel c2h2-type zinc-finger protein family

CATEGORY

transcription factor

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,nucleus

basic FUNCTION	may be involved in transcriptional regulation
	important factor involved in cell division during the early embryonic development of vertebrates
	key chromatin factor involved in maintaining P19 pluripotency and in the early mechanisms of neural differentiation but is dispensable in differentiated P19 cells

CELLULAR PROCESS

nucleotide, transcription, regulation

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

binding

RNA

small molecule	metal binding,
	Zn2+

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS