| basic FUNCTION
| involved in the specific inactivation of all-trans-retinoic acid to hydroxylated forms, such as 4-oxo-, 4-OH-, and 18-OH-all-trans-retinoic acid |
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maintains low levels of RA in the developing testes that blocks entry into meiosis and acts as a survival factor to prevent apoptosis of male germ cells  |
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with retinoic acid are critical regulators of osteogenesis in the axial skeleton |
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have a role in determining the cellular exposure to RA by inactivating RA in cells that do not need RA |
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in Sertoli cells acts as a masculinizing factor to arrest male germ cells in the G0 phase of the cell cycle and prevents them from entering meiosis, and thus is essential for the maintenance of the undifferentiated state of male germ cells during embryonic development |
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CYP26B1 and CYP26A1 are regulated by different nuclear receptors, resulting in tissue-specific expression patterns |
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plays a major role in the regulation of all-trans-retinoic acid metabolism and signaling in human aortic smooth muscle cells |
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P450 cytochrome enzyme that degrades retinoic acid (RA) |
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potentially regulated by activin, and involved in the control of granulosa cell proliferation |
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role for CYP26B1 in regulating RA-dependent signals in activated T cells but not during TGFB-dependent differentiation to Foxp3+ regulatory T cells |
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might establish and maintain synovial joint patency by restricting RA-mediated stimulation of chondrogenesis at borders of cartilaginous elements |
