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FLASH GENE

Symbol

OSR2

contributors: mct/pgu - updated : 28-02-2024

HGNC name	odd-skipped related 2 (Drosophila)
HGNC id	15830

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --low   highly methylated (85 p100 or more) in cancer cells (Gastric cancer)

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS

	mice lacking the transcription factor odd-skipped related-2 (Osr2) develop supernumerary teeth lingual to their molars because of expansion of the odontogenic field
	Osr2(-/-) mutant mice had only subtle defects in synovial joint development