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FLASH GENE

Symbol

PRUNE2

contributors: mct/npt - updated : 09-07-2015

HGNC name	prune homolog 2 (Drosophila)
HGNC id	25209

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --over   in neuroblastoma with favorable prognosis tumoral     --over   during NGF-depletion-induced apoptosis in neuroblastoma and was involved in the regulation of differentiation, survival, and aggressiveness of tumor cells (Valencia 2007) tumoral     --over   increased PRUNE2 protein expression may serve as a favorable prognostic marker in human leiomyosarcoma

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS