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FLASH GENE
Symbol ARID5A contributors: shn - updated : 07-01-2012
HGNC name AT rich interactive domain 5A (MRF1-like)
HGNC id 17361
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
Text highly expressed in cartilage and induced during chondrocyte differentiation
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies ortholog to Arid5a, Mus musculus
ortholog to Arid5a, Rattus norvegicus
ortholog to arid5a, Danio rerio
ortholog to ARID5A, Pan troglodytes
Homologene
FAMILY ARID5 subfamily
CATEGORY transcription factor
SUBCELLULAR LOCALIZATION     intracellular
basic FUNCTION
  • enhances chondrocyte-specific action of SOX9 (
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
  • promoter region of the Col2a1 gene (
  • RNA
    small molecule
    protein
  • SRY (sex determining region Y)-box 9, SOX9 (
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism SNP
  • Event-related brain oscillations evoked by visual oddball targets during P300 response (
  • Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS
  • Arid5a knockdown inhibited Col2a1 expression in chondrocytes (