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FLASH GENE
Symbol ARID5A contributors: shn - updated : 07-01-2012
HGNC name AT rich interactive domain 5A (MRF1-like)
HGNC id 17361
Location 2q11.2      Physical location : 97.202.463 - 97.218.370
Synonym name
  • modulator recognition factor I
  • modulator recognition factor 1
  • ARID domain-containing protein 5A
  • AT-rich interactive domain-containing protein 5A
  • RFVG5814
    • Synonym symbol(s) UNQ5814, MRF-1, MRF1, RP11-363D14
    DNA
    TYPE functioning gene
    STRUCTURE 29.00 kb     7 Exon(s)
    MAPPING cloned Y linked N status provisional
    Map cen - D2S2154 - D2S2159 - ARID5A - D2S113 - D2S2222 - qter
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    7 - 2223 - 594 - -
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    Text highly expressed in cartilage and induced during chondrocyte differentiation
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    interspecies ortholog to Arid5a, Mus musculus
    ortholog to Arid5a, Rattus norvegicus
    ortholog to arid5a, Danio rerio
    ortholog to ARID5A, Pan troglodytes
    Homologene
    FAMILY ARID5 subfamily
    CATEGORY transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    basic FUNCTION
  • enhances chondrocyte-specific action of SOX9 (
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
  • promoter region of the Col2a1 gene (
    • RNA
    small molecule
    protein
  • SRY (sex determining region Y)-box 9, SOX9 (
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism SNP
  • Event-related brain oscillations evoked by visual oddball targets during P300 response (
    • Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS
  • Arid5a knockdown inhibited Col2a1 expression in chondrocytes (