| basic FUNCTION
| converting uridine into pseudouridine after the nucleotide has been incorporated into RNA |
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can bind with nuclear receptors (NRs) and function as a coactivator through pseudouridylation and likely activation of an RNA coactivator called steroid receptor RNA activator (SRA1)  |
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PUS1 and PUS3 -dependent pseudouridylation of SRA1 is a highly complex posttranscriptional mechanism that controls a coactivator-corepressor switch in SRA1 with major consequences for nuclear receptor signaling |
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enzyme that converts uridine to Pseudouridine (Psi) in tRNA and other RNA |
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unusual site-specific modification enzyme in that it can modify a number of positions in tRNAs and can recognize several other types of RNA |
