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FLASH GENE
Symbol ACAA1 contributors: - updated : 13-10-2006
HGNC name acetyl-Coenzyme A acyltransferase 1 (peroxisomal 3-oxoacyl-Coenzyme A thiolase)
HGNC id 82
Location 3p22.2      Physical location : 38.164.201 - 38.178.733
Synonym name
  • 3-ketoacyl-CoA thiolase, peroxisomal precursor
  • beta- ketothiolase
    • Synonym symbol(s) PTHIO, THIO
    EC.number 2.3.1.16
    DNA
    TYPE functioning gene
    STRUCTURE 14.00 kb     12 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status confirmed
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    		N terminal thiolase domain
    HOMOLOGY
    Homologene
    FAMILY thiolase-like superfamily
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,peroxisome
    basic FUNCTION
  • acetyl-CoA acyltransferase,(peroxisomal matrix 3-oxoacyl-CoA thiolase), medium or long chain, catalyzing the fourth step of fatty acid beta-oxidation
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism energetic , lipid/lipoprotein
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS