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FLASH GENE

Symbol

FAM19A3

contributors: - updated : 21-11-2005

HGNC name	family with sequence similarity 19 (chemokine (C-C motif)-like), member A3
HGNC id	21590

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

DNA

TYPE	functioning gene
STRUCTURE	6.00 kb     5 Exon(s)

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed TAFA3.1 - - 1077 - 133 - Tom Tang using a different acceptor splice site for one of the coding exons compared to variant 2, resulting in a shorter isoform 1 than isoform 2 TAFA3.2 - - 1144 - 169 - Tom Tang encoding the longer isoform

EXPRESSION

Type

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Nervous brain forebrain cerebral cortex frontal     brain forebrain cerebral cortex parietal     brain forebrain cerebral cortex temporal     brain basal nuclei       Visual eye uvea choroid       eye retina

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Epithelial barrier/lining retinal pigment epithelium (RPE)

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

HOMOLOGY

Homologene

FAMILY

FAM19/TAFA family

CATEGORY

regulatory , signaling cytokine

SUBCELLULAR LOCALIZATION	extracellular
text	secreted

basic FUNCTION

may function as brain-specific chemokines or neurokines, that act as regulators of immune and nervous cells

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS