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FLASH GENE

Symbol

KDM2B

contributors: mct - updated : 24-11-2011

HGNC name	lysine (K)-specific demethylase 2B
HGNC id	13610

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --over   in various human leukemias

Susceptibility

Variant & Polymorphism

Candidate gene
Marker
Therapy target
	System Type Disorder Pubmed cancer     silencing KDM2B can help overcome resistant cancer cells for pro-apoptotic therapies

ANIMAL & CELL MODELS

about half of Fbxl10-deficient mice exhibit failure of neural tube closure, resulting in exencephaly and die shortly after birth