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FLASH GENE

Symbol

PF4

contributors: mct - updated : 25-01-2016

HGNC name	platelet factor 4
HGNC id	8861

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --over   in early growth of liposarcoma, mammary adenocarcinoma, and osteosarcoma

Susceptibility

Variant & Polymorphism

Candidate gene	potential biomarker of early tumor presence
Marker
Therapy target	several PF4 fragments and modified molecules exhibit antiangiogenesis properties and may become an alternative for further therapeutic angiogenesis

ANIMAL & CELL MODELS

NOA mice