| protein
| binding to EP300, FEN1 |
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regulating transcriptional coactivator TAF5L activity and promotes transcriptional repression |
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interacting with POLD3 (POLD3 plays a crucial role in the efficient recycling of PCNA during dissociation-association cycles of pol delta)  |
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stably interacts with NEIL1 (PCNA stimulates NEIL1 activity in excising the oxidized base 5-hydroxyuracil from single-stranded DNA sequences including fork structures) |
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intimate relationship between RBBP8 and PCNA may be important for the maintenance of genomic stability in higher eukaryotic organism |
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PCNA is protected by this newly identified partner molecule NUDT15, which is related to DNA synthesis and cell cycle progression |
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DTL recognizes an unusual degron, which is assembled specifically on chromatin via the binding of a specialized PIP box to PCNA |
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interacting with ATAD5 (plays an important role in PCNA deubiquitination in cooperation with the USP1-WDR48 complex) |
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during the DNA damage response, SETD8 interaction with PCNA through a specialized "PIP degron" domain targets it for PCNA-coupled DTL-dependent proteolysis |
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PARG interacts with PCNA, through a PCNA binding site and binding to PCNA contributes to PARG recruitment to DNA damage sites |
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BTBD12 could potentially interact with ubiquitylated FANCD2 or PCNA |
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HLTF promotes the Lys-63-linked polyubiquitination of proliferating cell nuclear antigen (PCNA) that is required for maintaining genomic stability |
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intracellular trafficking of KDM5C is controlled by its association with PCNA |
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DTL function is coupled to replication and repair because it only ubiquitinates substrates that associate with chromatin-bound PCNA |
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NCR2 interaction with PCNA inhibits NK cell function through NCR2/ITIM |
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ATM bind two regions in PCNA (stimulate DNA polymerase activity in a PCNA-dependent manner) |
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HMGN1 is a new PCNA-interacting protein that enhances the binding of PCNA to chromatin but not to purified DNA |
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importance of SUMO modification of PCNA in preventing replication fork collapse to DNA double-strand breaks and providing genome stability |
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SETD8 regulates the function of proliferating cell nuclear antigen (PCNA) protein through lysine methylation |
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disruption of the PCNA-binding motif impaired recruitment of UNG to S-phase replication foci, demonstrating that PCNA is a major factor for recruitment of UNG to unperturbed replication forks |
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protein that specifically recognizes ubiquitylated PCNA and plays an important role in cellular resistance to UV radiation |
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ZRANB3 is recruited by polyubiquitinated PCNA to promote fork restart following replication arrest |
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ZRANB3 can recognize K63-linked polyubiquitinated PCNA and plays an important role in restarting stalled replication forks |
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SPRTN acts at multiple steps in TLS, stabilizes RAD18 and ubiquitinated PCNA at damage sites, and facilitates the switch from replicative to TLS polymerase to bypass DNA lesion |
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KCTD13 is able to interact with MYBL2 and PCNA simultaneously |
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RAD18 is targeted to PCNA by DNA polymerase eta (POLH) |
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ROCK1 and ROCK2 could promote vascular smooth muscle cells (VSMC) proliferation through ERK nuclear translocation, regulating the expression of PCNA and cyclin D1 protein |
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ATAD5 is required for the regulation of chromatin-bound PCNA levels |
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important regulatory role of the USP1-WDR48 complex in HR (homologous recombination) repair through its regulation of the FANCD2-ubiquitinated (Ub) and PCNA-Ub cellular pools |
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ING1 interacts with the proliferating cell nuclear antigen (PCNA) in a UV-inducible manner |
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RTEL1-PCNA interaction promotes normal genome replication |
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DDB2 is a PCNA-binding protein, and that this association is required for DDB2 proteolytic degradation |
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SIVA1 interacts with RAD18 and serves as a molecular bridge between RAD18 and PCNA, thus targeting the E3 ligase activity of RAD18 onto PCNA |
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TRAIP (RNF206) is a novel PCNA-interacting factor that has important roles during mammalian replicative stress responses |
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SDE2 is a new genome surveillance factor regulated by PCNA interaction |
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NEIL1 interacts with essential replication proteins such as the ring-shaped homotrimeric proliferating cellular nuclear antigen (PCNA) |
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NEO1 is implicated in the maintenance of neural stem cells in the hippocampus by enhancing PCNA expressions |
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CHTF8-RFC1 is an alternative PCNA loader which plays important but poorly understood roles in multiple DNA replication-associated processes |
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N-terminus of USP1 is sufficient to engineer specificity in a more promiscuous USP, but is not required for direct PCNA or FANCI deubiquitination |
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