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FLASH GENE

Symbol

TRDV3

contributors: - updated : 26-01-2004

HGNC name	T cell receptor delta variable 3
HGNC id	12264

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

RNA

TRANSCRIPTS	type	messenger

EXPRESSION

Type

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol blood / hematopoietic thymus         Lymphoid/Immune lymph node

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Lymphoid         Lymphoid

cells

System Cell Pubmed Species Stage Rna symbol Lymphoid/Immune T cell

cell lineage

cell lines

fluid/secretion

at STAGE

physiological period

embryo, fetal

Text

thymocyte

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

a variable alpha domain, folded into a Ig-like domain with both ends joined by a disulfide bond

conjugated

GlycoP

HOMOLOGY

Homologene

FAMILY

immunoglobulin superfamily

CATEGORY

receptor membrane

SUBCELLULAR LOCALIZATION

extracellular

basic FUNCTION

antigen binding

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

immunity/defense

text	cellular immunity

PATHWAY

metabolism

signaling

a component

component of the T cell receptor, type 1, which is a disulfide bound heterodimer of a gamma and delta chains

INTERACTION

DNA

RNA

small molecule	other,
	binding fragmented antigens, mainly bacterial, in a MHC restricted way

protein

forming wih a TRGV protein, the binding site where the antigen is presented by a MHC molecule

cell & other

antigen presenting cells

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS