Selected-GenAtlas references SOURCE GeneCards NCBI Gene Ensembl IMGT
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol TRDV2 contributors: - updated : 26-01-2004
HGNC name T cell receptor delta variable 2
HGNC id 12263
DNA
TYPE functioning gene
SPECIAL FEATURE component of a cluster
text distal to TRAV@, proximal to TRDD/J/C@
STRUCTURE 0.00 kb     1 Exon(s)
MAPPING cloned Y linked N status confirmed
Map pter - TRDV3 - TRDC - TRDJ3 - TRDJ2 - TRDJ4 - TRDJ1 - TRDD3 - TRDD2 - TRDD1 - TRDV2 - cen
Authors Lefranc (03)
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestivepharynx   predominantly
Lymphoid/Immunelymph node    
 thymus   highly
 tonsils   highly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Lymphoid    
cells
SystemCellPubmedSpeciesStageRna symbol
Lymphoid/ImmuneT cell
cell lineage
cell lines
fluid/secretion blood
at STAGE
physiological period embryo, fetal
Text thymocyte
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a variable alpha domain, folded into a Ig-like domain with both ends joined by a disulfide bond
    • HOMOLOGY
    Homologene
    FAMILY immunoglobulin superfamily
    CATEGORY receptor membrane
    SUBCELLULAR LOCALIZATION extracellular
    basic FUNCTION antigen binding
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS immunity/defense
    text cellular immunity
    PATHWAY
    metabolism
    signaling
    a component component of the T cell receptor, type 1, which is a disulfide bound heterodimer of a gamma and delta chains
    INTERACTION
    DNA
    RNA
    small molecule other,
    binding fragmented antigens, mainly bacterial, in a MHC restricted way
    protein
  • forming wih a TRGV protein, the binding site where the antigen is presented by a MHC molecule
    • cell & other antigen presenting cells
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS