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FLASH GENE
Symbol NAGA contributors: - updated : 07-11-2006
HGNC name N-acetylgalactosaminidase, alpha-
HGNC id 7631
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularvesselscapillary   
Endocrineparathyroid   highly
Nervousbrain    
Reproductivefemale systemplacenta  highly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Connectivebone  highly
Epithelialbarrier/liningendothelium  
Nervouscentral   
Nervousperipherous   
cells
SystemCellPubmedSpeciesStageRna symbol
Cardiovascularendothelial cell
Nervousneuron
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
17 AAs signal peptide, six N glycosylation sites
isoforms Precursor
HOMOLOGY
Homologene
FAMILY glycosyl hydrolase 27 family
CATEGORY enzyme
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,organelle,lysosome
basic FUNCTION
  • catalyzing the degradation of alpha-N-acetylgalactosaminyl-containing glycoconjugates
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    Other targeted to the lysosome by M6P receptor mediated pathway
    ASSOCIATED DISORDERS
    corresponding disease(s) NAGA , SCHND1
    related resource Schindlerdisease
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS